Primary autoimmune haemolytic anaemia in the dog
Bennett, D.; Finnett, S.L.; Nash, A.S.; Kirkham, D.
Veterinary Record 109(8): 150-153
1981
ISSN/ISBN: 0042-4900 PMID: 7324359 Document Number: 169235
In 19 cases of primary autoimmune haemolytic anaemia, clinical features included pale mucous membranes, weakness, lethargy and collapse. The intravascular haemolytic type of the disease was seen in nine cases and was characterized by evidence of haemolysis (e.g. marked bilirubinaemia). The other 10 cases were classed as the extravascular destructive type. Autoantibodies (of the IgG class) and complement (C3) on the red blood cells from affected patients were demonstrated by a commercial Coombs' (antiglobulin) test which was satisfactory in association with clinical, haematological and biochemical features. Treatment with prednisolone was successful in most cases.