Physico-chemical, mutagenic and carcinogenic properties of nitrosated urea herbicide metabolites

Warzok, R.; Mendel, J.; Thust, R.; Schwarz, H.; Schneider, J.

Iarc Scientific Publications 31: 685-691

1980


ISSN/ISBN: 0300-5038
PMID: 7228290
Document Number: 168127
Alkylating activities, rates of decomposition, partition coefficients (octanol/water) and sister chromatid exchanges of several N-nitroso compounds, formed by nitrosation of pesticide metabolites or closely related substances, were determined. The carcinogenic activity of two compounds was investigated in rats. The measured parameters were compared in a search for possible correlations.

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