Effects of dietary protein and fat sources on plasma cholesterol parameters, LCAT activity and amino acid levels and on tissue lipid content of growing pigs
Forsythe, W.A.; Miller, E.R.; Hill, G.M.; Romsos, D.R.; Simpson, R.C.
Journal of Nutrition 110(12): 2467-2479
1980
ISSN/ISBN: 0022-3166 PMID: 7441375 Document Number: 166911
Effects of dietary protein and fat sources on plasma cholesterol were tested with young male pigs. Diets providing 16 and 42% of metabolizable energy from protein and fat, respectively, were eaten for 12 to 14 weeks. Protein was derived from plant sources, 50% from soya bean meal and 25 each from maize and wheat, or from animal sources, 90% from casein and 10 from lactalbumin. The polyunsaturated to saturated fat ratio in the diets was on average 3.0 in the polyunsaturated fat diets and 0.3 in the saturated fat diets. Cholesterol content of the 4 experimental diets (plant protein-polyunsaturated fat; plant protein-saturated fat; animal protein-polyunsaturated fat; animal protein-saturated fat) was 0.6 mg/kcal. Intake of diets containing plant protein rather than animal protein reduced total plasma cholesterol concentrations by 50 mg/100 ml; high-density lipoprotein (HDL) cholesterol values were also decreased in pigs given plant protein. Similarly, plasma cholesterol values were about 40 mg/100 ml lower in pigs on the polyunsaturated fatty acid diets than in pigs on the saturated fat diets. HDL cholesterol concentrations, however, were unaffected by source of dietary fat.