Morphologic manifestations of intercellular interaction in the organs of immunogenesis
Salov, V.F.; Karpov, V.S.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1980(6): 54-57
1980
ISSN/ISBN: 0372-9311 PMID: 6969504 Document Number: 166844
The morphological manifestations of intercellular contacts in guinea pigs after the s.c. injection of 0.1 mg of BCG culture were studied by transmission and scanning electron microscopy. The morphological links between T cells and B lymphocytes, between B lymphocytes and macrophages, as well as among individual macrophages, were revealed. The intracellular links had different morphological manifestations depending on the type of cells and their localization in the organ. Thus, in the capillary lumen and the thymus cavity the formation of cytoplasmic bridges between these cells was revealed; in the stroma of the organ the formation of linking structures, similar to closing plates, between lymphocytes was observed. An increase in the number of micropinocytosis bubbles in the contact zone indicated the increased permeability of the cytoplasmic membrane and the intensified exchange processes between the cells.