Diagnostic Value of Pleural Fluid Adenosine Deaminase in Tuberculous Pleuritis at Thammasat University Hospital
Saiphoklang, N.; Kanitsap, A.; Ruchiwit, P.
Journal of the Medical Association of Thailand 99 Suppl. 4: S1-S9
2016
ISSN/ISBN: 0125-2208 PMID: 29916665 Document Number: 16639
Pleural fluid adenosine deaminase (ADAPF) is a diagnostic test for diagnosing the early tuberculous pleuritis (TBP). However, cutoff values vary widely in many studies. To determine the optimal diagnostic value of ADAPF. A prospective study was performed between August 2012 and August 2014. One hundred seventyeight patients with pleural effusions; 29 TBPs, 63 malignant pleural effusions (MPEs), 40 parapneumonic effusions (PARAEs), 18 transudates, 5 empyemas, 19 other exudates, and 4 unknown causes, were investigated. Mean + SD of ADAPF was 60.0+25.6 U/L with TBPs, 15.6+11.1 U/L with MPEs, 15.8+9.9 U/L with PARAEs, Pleural fluid ADA assay is a helpful diagnostic tool with high sensitivity and specificity for the rapid diagnosis of TBP.