Clavulanic acid and amoxycillin: a clinical, bacteriological, and pharmacological study
Ball, A.P.; Geddes, A.M.; Davey, P.G.; Farrell, I.D.; Brookes, G.R.
Lancet 1(8169): 620-623
1980
ISSN/ISBN: 0140-6736 PMID: 6102627 Document Number: 165155
Clavulanic acid is an inhibitor of certain .beta.-lactamases, notably those enzymes which inactivate the penicillins and cause resistance of important bacteria to these antibiotics. Microbiological, pharmacological and clinical studies show that clavulanic acid in combination with amoxycillin is effective and safe in the treatment of urinary-tract infection caused by amoxycillin-resistant bacteria.
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