Serum theophylline levels in adult asthmatics: comparison of oral sustained-release and microcrystalline preparations
Jones, D.T.; Sears, M.R.
New Zealand Medical Journal 92(667): 196-198
1980
ISSN/ISBN: 0028-8446 PMID: 6933358 Document Number: 163884
Serial serum theophylline levels were measured in 20 inpatient asthmatics given tablets of either microcrystalline or sustained-release theophylline. The sustained-release preparation gave serum levels which were more consistently within the therapeutic range with a significantly higher trough concentration. No increase in adverse effects was encountered.
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