Sympathetic-adrenal system in various types of anesthesia in surgical treatment of gastric and rectal cancer
Aleksandrin, G.P.; Smirnova, E.V.; Frid, I.A.
Voprosy Onkologii 26(11): 44-49
1980
ISSN/ISBN: 0507-3758 PMID: 7456425 Document Number: 163861
Under study was the functional activity of the sympatho-adrenal system in identical surgical interventions in 44 gastric cancer patients and 77 rectal cancer patients, operated under nitrogen monoxide-ether, nitrogen monoxide-fluothane anesthesia and under neuroleptanalgesia supplemented with nitrogen monoxide. The sympatho-adrenal activity was assessed, taking into account the content of total catecholamines (adrenaline and noradrenaline) in blood and urine prior to surgery, intraoperatively before anesthesia, during the most traumatizing moment of the operation and at 1, 3, 6 day after it. It was found that in identical operative procedures stimulation of the sympatho-adrenal system is mostly manifest in patients operated upon under either anesthesia and neuroleptanalgesia. Use of fluothane narcosis in gastric cancer patients produced no marked activation of the sympatho-adrenal system, while in rectal cancer patients it was not so significant as in either narcosis and neuroleptanalgesia.