Effect of monosodium glutamate on the activity of alkaline phosphatase

Omran, R.G.; Dhindsa, K.S.; Bhup, R.

Indian Journal of Experimental Biology 18(12): 1436-1438

1980


ISSN/ISBN: 0019-5189
PMID: 7228131
Document Number: 162617
Monosodium glutamate (MSG), a commonly used flavor enhancer, inhibited alkaline phosphatases from chicken, pigeon, rat and rabbit intestine besides human placenta and mouse kidney in an uncompetitive manner. Inhibition of alkaline phosphatase by MSG could be a major factor in limiting amount of inorganic phosphate needed for bone ossification and calcification.

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