A new method for measurement of human thyroid-stimulating immunoglobulins

Kleinmann, R.E.; Braverman, L.E.; Vagenakis, A.G.; Butcher, R.W.; Clark, R.B.

Journal of Laboratory and Clinical Medicine 95(4): 581-589

1980


ISSN/ISBN: 0022-2143
PMID: 6244354
Document Number: 162518
Measurement of human TSI AMP generated in the presence of Ig from normal subjects in the same assay. By this method, sera from 86% of patients with untreated thyrotoxic Graves' disease were positive for TSI. This rapid, sensitive assay for TSI has the potential of being adapted for use in more general clinical laboratories.

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