Antibacterial Activity of Excretions-Secretions from Chrysomya megacephala Against Escherichia coli
Chaiwong, T.; Srivoramas, T.; Sebsumran, P.; Panya, M.; Wanram, S.; Panomket, P.
Journal of the Medical Association of Thailand 99(Suppl 1): S7-11
2016
ISSN/ISBN: 0125-2208 PMID: 26817232 Document Number: 16220
The blowfly, Chrysomya megacephala, is distributed worldwide. Previous studies found maggot excretions-secretions from other blowfly species inhibited pro-inflammatory response and antimicrobial activity. This study aimed to test the bactericidal activity of excretions-secretions from C. megacephala larvae. A total of 1,500 3-day-old larvae were used to collect excretions-secretions (ES) modified by the Barnes method. The bactericidal activity ofthe excretions-secretions was test by Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli using suitable liquid culture assay. Scanning electron microscope (SEM) was used to investigate the morphological change ofthe bacteria. E. coli were significantly inhibited by excretions-secretions from C. megacephala larvae. P. aeruginosa and S. aureus were not found to inhibit growth. The excretions-secretions from C. megacephala larvae may have a medical property for the inhibition of bacterial growth.