Fibrolamellar hepatocellular carcinoma in a Thai man who presented with hypoglycemia: case report and review of literature
Tangkijvanich, P.; Thong-Ngam, D.; Kullavanijaya, P.; Suwangool, P.
Journal of the Medical Association of Thailand 83(7): 809-816
2000
ISSN/ISBN: 0125-2208 PMID: 10932518 Document Number: 1622
We present a case of fibrolamellar hepatocellular carcinoma (FLHCC) in a 22 year old Thai man whose presenting symptom was hypoglycemic coma with right hemiparesis. The serum marker for hepatitis B virus (HBsAg) was positive and serum AFP was very high (over 100,000 IU/ml). The abdominal ultrasonography revealed a solitary heterogenic mass, size 5.5 x 6.5 cm in the right lobe. Chest X-ray showed multiple lung metastases. Ultrasound-guided needle liver biopsy was performed and typical histologic features of FLHCC in non-cirrhotic liver were diagnosed. The patient's comatose state and neurological deficits recovered rapidly after glucose administration. Unfortunately, the tumor mass could not be resected on account of far-advanced stage with metastases. Here, we also review of the literature concerning FLHCC in many aspects.
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