Biochemical and cytokinetic patterns in the growth of a transplanted pigmented melanoma
Bogdanov, G.N.; Konovalova, N.P.; Goncharova, S.A.; Shtol'ko, V.N.; Vasil'eva, L.S.
Voprosy Onkologii 26(3): 45-49
1980
ISSN/ISBN: 0507-3758 PMID: 7368657 Document Number: 161813
Under study were biochemical and cytokinetic patterns of the pigmented melanoma growth in mice. The data obtained allows a conclusion that there is a relationship between the process of melanogenesis and proliferative activity of the tumor tissue. A delayed tumor growth beyond the peak point due to the reduced proliferative pool and increased cell losses is accompanied with a fall in the activity of the key enzyme of melanogenesis and the reduced level of melanoproteids.