Pregnancy complicated by the Kasabach-Merritt syndrome
Phillippe, M.; Acker, D.; Frigoletto, F.D.
Obstetrics and Gynecology 56(2): 256-258
1980
ISSN/ISBN: 0029-7844 PMID: 7190257 Document Number: 161233
The Kasabach-Merritt syndrome is the association of cavernous hemangiomas and consumption coagulopathy marked by anemia, thrombocytopenia, and hypofibronigenemia. Exacerbation of the consumption coagulopathy has been described in the 2 previous reports of this syndrome when associated with pregnancy. The authors report a third patient whose delivery and postopartum course were marked by increased coagulation abnormalities and subsequent hemorrhage. This patient's 32-day hospital course and need for multiple blood transfusions, clotting factors, platelets, heparin, and finally epsilon-aminocaproic acid underscore the need for patients with this syndrome to deliver in a referral center hospital where replacement therapy and hematologic consultation are readily available.