Use of labetalol hydrochloride by continuous infusion in managing the hypertensive state; a clinical case
Mereto, G.C.; Garavini, L.
Minerva Anestesiologica 46(3): 441-448
1980
ISSN/ISBN: 0375-9393 PMID: 7443061 Document Number: 161170
A case of acute dissecting aneurysm of the aorta in a seriously hypertensive woman was treated for 9 days with continuously infused labetalol hydrochloride, initially at 1 mg/min and later at 125 mg/min. Continuous, invasive monitoring of arterial pressure showed values to be within present safety limits, even though the treatment was first supplemented with furosemide and then with clonidine. The use of labetalol in hypertension emergencies offers and alternative to the employment of dangerous drugs that have a transient effect, or are even unadvisable for treatments lasting longer than two days.