Effect of resection of the primary focus on matastasis of transplantable tumors
Kozlov, A.M.; Sof'ina, Z.P.
Voprosy Onkologii 26(7): 43-46
1980
ISSN/ISBN: 0507-3758 PMID: 7405103 Document Number: 160785
The rate of metastasization was estimated by calculating the coefficients of the metastases involved lung mass and the number of metastatic nocules. The experiments with melanoma B-16 and Lewis carcinoma have shown a marked stimulating effect of removing the primary tumor node on metastases growth, the number of metastatic nodules in the lung being less compared with control, but these were larger. In experiments with carcinoma RL-67 the removal of the primary node would not stimulate the growth of metastases. Adenocarcinoma 755 showing no metastases in routine percutaneous inoculation would not give metastases too after the removal of the primary tumor.