Fatty acid makeup of the high-density lipoproteins in hyperalphalipoproteinemia
Gerasimova, E.N.; Torkhovskaia, T.I.; Ozerova, I.N.; Khaltaev, N.G.; Metel'skaia, V.A.
Voprosy Meditsinskoi Khimii 26(5): 650-656
1980
ISSN/ISBN: 0042-8809 PMID: 7423882 Document Number: 160564
An increase in the ratio of free cholesterol/phospholipids as well as in proportional content of oleic and linoleic acids were observed in lecithins of high density lipoproteins (HDL) from the 409-59 years old patients with hyper-alpha-lipoproteinemia. Activity of lecithine-cholesterol acyltransferase was also increased in blood plasma while the HDL cholesterol content increased. The data obtained suggest alterations in physicochemical properties of HDL and their effect on lecithine-cholesterol acyltransferase activity under conditions of hyper-alpha-lipoproteinemia.