Comparative evaluation of the treatment of radiation skin injuries with oxycort ointment and Peruvian balsam
Nikulin, A.A.; Krylova, E.A.
Farmakologiia i Toksikologiia 43(1): 97-100
1980
ISSN/ISBN: 0014-8318 PMID: 7379999 Document Number: 159874
The regenerating action of Peruvian balm and oxycort was compared in experiments on rats with experimental radiation skin injuries. Radiation skin ulcers entailed severe morphological and biochemical abnormalities, there was also observed an unstable healing provided the treatment was not applied. Oxycort ointment slightly reduced the period of healing. However, formation of secondary microdefects was conducive to recurrent ulcer in the future. Peruvian balm exerted a pronounced bactericidal action, strongly intensified the reparative processes, and, therefore, reduced the period of healing and favoured the differentiation of the cicatricial tissues that led to a stable healing of the ulcers.