Investigations concerning the action of serveral chemical and biological agents on HBsAg
Morfei, A.; Burducea, O.; Neuman, R.; Cajal, N.; Copelovici, Y.; Crişan, I.
Virologie 31(4): 273-278
1980
ISSN/ISBN: 0253-181X PMID: 7257176 Document Number: 159390
Native and purified HBsAg preparations were subjected in vitro to the action of cetylpyridinium bromide (Bromocet), hibitan-chlorhexidine (Hibiscrub), chloramine B and propolis extract, at different concentrations and for various time intervals. The effect of these agents on the serological reactivity of HBsAg was tested by electroimmunodiffusion (EID) and radioimmunoassay (RIA). Chloramine B and the propolis extract had a significant inhibitory effect-ascertained by both EID and RIA - on purified HBsAg, but not on the native preparation. The inhibition exerted by Bromocet and Hibiscrub indicated by EID results was not confirmed by RIA.