Effect of tunicamycin and neuraminidase on the expression of Fc-IgM and -IgG receptors on human lymphocytes

Itoh, K.; Kumagai, K.

Journal of Immunology 124(4): 1830-1836

1980


ISSN/ISBN: 0022-1767
PMID: 6965963
Document Number: 159155
Using a rosette technique with ox red blood cells (ORBC) coated with rabbit Ig cells. The expressions of IgM- and IgG-Fc receptors on human T, and probably non-T, lymphocytes in culture even under nonstimulating conditions change in opposite directions, and protein glycosylation in the cell membrane may be a common factor influencing the expression of Fc receptors. This is necessary for the structure of IgM receptors, but unnecessary for the structure of IgG receptors to exert a receptor activity.

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