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Lincomycin concentration in the blood and tissues when administered by electrophoresis in children with acute and chronic hematogenic osteomyelitis

Kelimbetov, Z.K.; Makarenkova, R.V.; Davydov, V.A.; Ergaliev, A.E.

Antibiotiki 25(8): 626-629

1980

ISSN/ISBN: 0003-5637
PMID: 7406476
Document Number: 158991
Twenty five children suffering from acute and chronic hematogenic osteomyelitis were subjected to lincomycin therapy in addition to surgical and general tonic treatment. The antibiotic was administered by means of electrophoresis in 15 children and by means of electrophoresis together with intramuscular injections in 10 children. It was found that administration of the drug by means of electrophoresis 1 hour after its intramuscular injection provided the highest lincomycin levels in the bone cavity favourable for the disease treatment.

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