Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effects of variations in nucleoside pool sizes on comparisons of the incorporation of [3H]thymidine into isolated rat liver cells

Russell, G.R.; Partick, E.J.

Cancer Research 40(10): 3719-3722

1980

ISSN/ISBN: 0008-5472
PMID: 7438055
Document Number: 157958
Isolated rat liver cells have been used to measure DNA repair synthesis induced by ultraviolet light and aflatoxin. Age, sex, and diet of the rats were found to influence DNA repair in rat liver cells, as measured by [3H]thymidine uptake by the cells. These effects were found to be due to variations in the thymidine pool size and should serve to indicate that high-specific-activity thymidine (i.e., low nucleoside concentrations) is subject to artifacts generated by pool size variations.

Document emailed within 1 workday
Secure & encrypted payments

Guidoux, S.; Schimpff, R.M.; Garnier, P.E.; Nahoul, K.; Evain Brion, D.; Job, J.C. 1984: Effects of sexual steroids on thymidine incorporation in human lymphocytes and on serum so-called thymidine activity Pathologie-Biologie 32(8): 884-887
Dolo, V.; Pizzurro, P.; Ginestra, A.; Vittorelli, M.L. 1995: Inhibitory effects of vesicles shed by human breast carcinoma cells on lymphocyte 3H-thymidine incorporation, are neutralised by anti TGF-beta antibodies Journal of Submicroscopic Cytology and Pathology 27(4): 535-541
Keĭlis-Borok, I.V.; Latsinik, N.V.; Deriglazova, I.F. 1972: Characteristics of bone marrow cells--precursors of fibroblast-like cells according to their incorporation of thymidine-h 3 Biulleten' Eksperimental'noi Biologii i Meditsiny 73(10): 91-93
Laurent, G.; Laduron, C.; Ruysschaert, J.M.; Deleers, M. 1981: Inhibition of cationic liposomes of [3H]thymidine incorporation into DNA of L1210 cells Research Communications in Chemical Pathology and Pharmacology 31(3): 515-527
Zamaraeva, E.V. 1989: 3H-thymidine incorporation by interstitial myocardial cells in the rat with a single administration of the label Biulleten' Eksperimental'noi Biologii i Meditsiny 108(12): 739-741
Polishchuk, A.M.; Miagkaia, T.T.; Gunderina, L.I. 1971: Rate of incorporation of H3-thymidine into diploid and tetraploid cell nuclei of rat regenerating liver throughout the S-period Tsitologiia 13(10): 1225-1232
Lee, D.J.; Prensky, W.; Krause, G.; Hughes, W.L. 1976: Blood thymidine level and iododeoxyuridine incorporation and reutilization in DNA in mice given long-acting thymidine pellets Cancer Research 36(12): 4577-4583
Ochi, T.; Takahashi, K.; Ohsawa, M. 1983: A mechanism for the stimulation by inorganic mercury of [3H] thymidine incorporation into DNA in cultured Molt-4F cells Japanese Journal of Experimental Medicine 53(4): 187-194
Neustroev, G.V.; Petrov, K.I. 1978: Effect of an erythrocyte inhibitor on the in vitro incorporation of thymidine into the DNA of bone marrow cells Tsitologiia 20(2): 179-183
Lameh, J.; Chuang, L.; Israel, M.; Chuang, R. 1990: Effect of N-trifluoroacetyladriamycin-14-O-hemiadipate (AD 143) on the incorporation of 3H-thymidine and 3H-uridine and on the cell cycle progression of human cells in culture Proceedings of the Western Pharmacology Society 33: 99-103
Allison, D.C.; Ridolpho, P.F.; Anderson, S.; Bose, K. 1985: Variations in the [3H]thymidine labeling of S-phase cells in solid mouse tumors Cancer Research 45(12 Part 1): 6010-6016
Balzarini, J.; De Clercq, E. 1987: Differential affinities of pyrimidine nucleoside analogues for deoxythymidine and deoxycytidine kinase determine their incorporation into murine leukemia L1210 cells Acta Biochimica Polonica 34(2): 63-77
Mironescu, S.G.; Epstein, S.M.; DiPaolo, J.A. 1980: Relationship between morphological transformation and [3H]thymidine incorporation stimulated by a chemical carcinogen in postconfluent cultures of hamster embryo cells Cancer Research 40(7): 2411-2416
Ruscetti, S.K. 1986: Employment of a [3H]thymidine-incorporation assay to distinguish the effects of different Friend erythroleukemia-inducing retroviruses on erythroid cell proliferation Journal of the National Cancer Institute 77(1): 241-245
Klein, A.; Madeja, Z.; Guzik, K. 1991: 3H-thymidine incorporation method versus colony forming assay in the determination of anchorage-independent cell growth of rat sarcoma (XC) and Morris hepatoma 7777 (MH) cells Folia Histochemica et Cytobiologica 29(2): 75-80
Sakata, R. 1975: Induction of ornithine decarboxylase, tyrosine aminotransferase, and thymidine kinase by glucocorticoid in isolated, perfused liver after tumor inoculation Gan 66(3): 245-252
Morstyn, G.; Kinsella, T.; Shan, C.S.; Whang-Peng, J.; Russo, A.; Mitchell, J.B. 1985: In vivo incorporation of bromodeoxyuridine into proliferating cells in the marrow and its effects on granulocyte-macrophage progenitor cells Experimental Hematology 13(4): 289-294
Ciesielski-Treska, J.; Sensenbrenner, M. 1970: Autoradiographic study of the incorporation of tritiated uridine in isolated cells of spinal ganglia in culture Journal de Physiologie 62 Suppl 2(2): 261
Cass, C.E.; Dahlig, E.; Lau, E.Y.; Lynch, T.P.; Paterson, A.R. 1979: Fluctuations in nucleoside uptake and binding of the inhibitor of nucleoside transport, nitrobenzylthioinosine, during the replication cycle of Hela cells Cancer Research 39(4): 1245-1252
Adzhimolaev, T.A.; Bezruchko, S.M.; Vozhenina, N.I. 1972: Effect of electric stimulation on the incorporation of H3-uridine and H3-lysine into cells of Tritonia isolated nervous system Biofizika 17(1): 77-84