Diagnostic value of detecting neutralizing antibodies to Coxsackie B enteroviruses in patients with infectious-allergic myocarditis
Antsupova, A.S.; Troitskaia, M.V.; Zvereva, K.V.; Vostokova, A.A.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 40-42
1980
ISSN/ISBN: 0372-9311 PMID: 6250306 Document Number: 157573
The clinical virological survey of 180 cardiological patients aged 16-60 years with clinically diagnosed infectious allergic myocarditis (100), rheumatism (38) and other cardiac diseases (42) was made. A group of 97 practically healthy adults aged 21-60 years was used for control. The survey revealed statistically significant differences in the frequency of occurrence of Coxsackie B virus in healthy persons and in cardiac patients. Thus the criteria of the diagnostic significance of the results of the serologic survey gave grounds for suspicion that diseases in 31.2% of the surveyed patients were connected with the presence of Coxsackie B virus infection. Significantly more frequently Coxsackie B virus infection (predominantly type 4 virus) was found to be associated with infectious allergic myocarditis (42%).