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Treatment of chronic urticaria with an inhibitor of complement activation (cinnarizine)

Kalimo, K.; Jansen, C.T.

Annals of Allergy 44(1): 34-37

1980

ISSN/ISBN: 0003-4738
PMID: 7352689
Document Number: 157370
Twenty-three patients with chronic urticaria were treated with cinnarizine, dexchlorpheniramine and placebo in a double-blind, crossover trial. Compared to placebo treatment both cinnarizine and dexchlorpheniramine caused a statistically significant improvement in the clinical symptoms (p less than 0.01). The two active drugs were found to be equally effective; however, cinnarizine was better tolerated. Both drugs appear to be useful in the treatment of chronic urticaria.

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