The use of cyclosporine in dermatology
Dehesa, L.; Abuchar, A.; Nuno-Gonzalez, A.; Vitiello, M.; Kerdel, F.A.
Journal of Drugs in Dermatology Jdd 11(8): 979-987
2012
ISSN/ISBN: 1545-9616 PMID: 22859244 Document Number: 15651
Cyclosporine is an immunosuppressive drug that acts selectively on T-cells by inhibiting calcineurin phosphorylase. It has been used in dermatology since its approval for US Food and Drug Administration in 1997 for the use in psoriasis. While indicated only for the treatment of moderate to severe psoriasis, cyclosporine has also been used as an off-label drug for the treatment of various inflammatory skin conditions, including atopic dermatitis, blistering disorders, and connective tissue diseases. In this article, we review the use of cyclosporine in dermatology.
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