The treatment outcome of radical radiotherapy in laryngeal cancer
Chitapanarux, I.; Tharavichitkul, E.; Chakrabandhu, S.; Klunklin, P.; Onchan, W.; Pukanhapan, N.; Srikawin, J.; Sittitrai, P.; Vongtama, R.
Journal of the Medical Association of Thailand 97(1): 101-106
2014
ISSN/ISBN: 0125-2208 PMID: 24701736 Document Number: 15639
This study reports the treatment outcome of radiotherapy alone for laryngeal cancer A retrospective analysis was performed on 138 patients with stage I to IV squamous cell carcinoma of larynx who received radiotherapy alone in Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Thailand between 2003 and 2009. The 4-year local control (LC) rate in all patients was 44.1%. The 4-year overall survival (OS) was 82.1%. The 4-year LC rates for stage I, II, III, and IV were 75.3%, 69.4%, 57.1%, and 36.9%,respectively (p = 0.0055). Finally, the 4-year OS rates for stage I, II, III, and IV were 85%, 78.6%, 91.1%, and 71.5%, respectively. The laryngeal preservation rate of all stages was 73%. In conclusion, the treatment outcome of radiotherapy alone in all stages of laryngeal cancer in our center was unsatisfactory when compared to other series.
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