Immunoglobulins in cerebrospinal fluid in various neurologic disorders
Bouloukos, A.; Lekakis, J.; Michael, J.; Kalofoutis, A.
Clinical Chemistry 26(1): 115-116
1980
ISSN/ISBN: 0009-9147 PMID: 7356542 Document Number: 155465
We determined the concentrations of immunoglobulins A, G, and M in cerebrospinal fluid of 16 patients suffering from multiple sclerosis, 13 with non-bacterial meningitis, 10 with stroke syndrome, and 13 with epilepsy. The differences in concentrations of immunoglobulins in these groups were remarkable in the patients with multiple sclerosis, meningitis, or stroke syndrome. We propose that the determination of the absolute immunoglobulin content in cerebrospinal fluid is of greater significance than the relative immunoglobulin concentration.