HDL-cholesterol and ischaemic cardiovascular disease in the Copenhagen city heart study
Jensen, G.; Schnohr, P.; Faergeman, O.; Meinertz, H.; Nyboe, J.; Hansen, A.T.
Danish Medical Bulletin 27(3): 139-142
1980
ISSN/ISBN: 0907-8916 PMID: 7438798 Document Number: 155314
In a randomly selected subsample of 1615 men and women participating in a cardiovascular survey which included screening for ischaemic cardiovascular disease (ICVD) and cardiovascular risk factors, total cholesterol and high-density lipoprotein (HDL) cholesterol were estimated and the ratio of total cholesterol to HDL cholesterol (Rc) was calculated. Of 557 men 107 and 721 women 94 had signs of ICVD. In women, total cholesterol and Rc were significantly more and HDL cholesterol was significantly less in afflicted than in nonafflicted and the trend, although not significant, was the same in the men. The Rc gave the best separation between afflicted and nonafflicted. In nonafflicted women, there was a significant correlation between Rc and relative weight. In nonafflicted men, there was a significant correlation between Rc and relative weight or alcohol intake. In neither sex was there any correlation between Rc and blood pressure, smoking or physical exercise.