A lowering of the risk of ischaemic heart disease among the population (according to the results of the Kaunas preventive study)
Glazunov, I.S.; Baubinene, A.V.; Domarkene, S.B.; Grabauskas, V.I.; Kuzminskis, V.V.; Prokhorskas, R.P.; Misjavicene, I.S.
Cor et Vasa 24(4): 233-239
1982
ISSN/ISBN: 0010-8650 PMID: 7140305 Document Number: 183435
Out of the total number of 2455 individuals who had passed a primary screening, a group of men aged 45-59 yr, with average (borderline) values of arterial pressure (AP), serum cholesterol (CH) and glucose levels after the glucose load, was selected for studies of potential lowering of the level of risk factors of ischemic heart disease (IHD) among the population, and for elaboration of a model of multifactorial prevention. The enrollment of the probands lasted 9.4 mo. on the average (.+-. 6.0 mo.); the preventive double-blind study proper lasted 12 mo. The levels of the 3 specified risk factors sank both during the enrollment period and during the proper 1-yr preventive therapy period. The risk factor levels were substantially lowered both in consequence of repetitive regular examinations and by the action of drug treatment (this applies especially to the CH level). In the evaluation of the results of the preventive study, the effects of the lowering of the AP and of the CH and glucose levels even to the average values must be taken into account. It is possible to lower the risk of IHD among the population.