Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of some lipophilic substances on mitochondrial ATPase

Casali, C.; Degli Esposti, M.; Bertoli, E.; Parenti-Castelli, G.; Lenaz, G.

Bollettino della Societa Italiana di Biologia Sperimentale 56(10): 996-1001

1980

ISSN/ISBN: 0037-8771
PMID: 6449955
Document Number: 155295
This work reports a study about the influence of some lipophilic substances like cholesterol, calciferol and tocopherol on the ATP-hydrolase activity in mitochondria. It is found that the steroids cholesterol and calciferol inhibit ATPase activity and behave like uncompetitive factors towards the enzymatic kinetics. Tocopherol, instead, affects significantly only the DCCD sensitivity of ATPase. Such effects are very probably due to the action of the physico-chemical state of th mitochondrial membrane produced by these lipophilic compounds.

Document emailed within 1 workday
Secure & encrypted payments

Lores Arnaiz, G.R.; Gómez de Lima, M.A. 1981: The effect of several neurotransmitter substances on nerve ending membrane ATPase Acta Physiologica Latino Americana 31(1): 39-44
Ulasevich, I.I.; Pechenina, M.I. 1974: Effect of vitamins e and K on the mitochondrial ATPase activity in the skeletal muscles and liver of white rats Voprosy Meditsinskoi Khimii 20(2): 163-165
Lindenborn-Fotinos, J.; Sayers, T.J.; Berg, P.A. 1982: Mitochondrial antibodies in primary biliary cirrhosis. VI. Association of the complement fixing antigen with a component of the mitochondrial F1-ATPase complex Clinical and Experimental Immunology 50(2): 267-274
Pansini, A.; Guerrieri, F.; Papa, S. 1976: Action of lipophilic cations on the protonic conduction in the internal mitochondrial membrane Bollettino della Societa Italiana di Biologia Sperimentale 52(19): 1645-1651
Sahach, V.F.; Vavilova, H.L.; Rudyk, O.V.; Strutyns'ka, N.A. 2003: Release of unidentified substances of mitochondrial origin--evidence of mitochondrial permeability transition pore opening in the heart mitochondria of rats Fiziolohichnyi Zhurnal 49(5): 3-12
Wysocki, P.; Kwaszewska, A.K.; Szewczyk, E.M. 2011: Influence of substances produced by lipophilic Corynebacterium CDC G1 ZMF 3P13 on the microorganisms inhabiting human skin Medycyna Doswiadczalna i Mikrobiologia 63(1): 45-52
Kuzela, S.; Kolarov, J.; Krempaský, V.; Luciaková, K.; Ujházy, V. 1978: Mitochondrial ATPase of Zajdela hepatoma. V. Mitochondria of Zajdela hepatoma contain membrane sectors of ATPase complex unassociated with F1 Neoplasma 25(6): 745-749
Uhlig, G.; Kolb, E.; Schineff, C. 1984: Activity and various properties of Mg-ATPase, Na,K-ATPase, Ca-ATPase and HCO3-ATPase in the kidney cortex, parotid gland and pancreas of cattle Archiv für Experimentelle Veterinarmedizin 38(4): 572-582
Akimenko, V.K.; Minkov, I.B.; Vinogradov, A.D. 1971: Action of uncouplers on soluble mitochondrial ATPase Biokhimiia 36(3): 655-658
Dubiel, W.; Henke, W.; Miura, Y.; Holzhütter, H.G.; Gerber, G. 1987: Identification and characteristics of a novel mitochondrial ATPase in rat liver Biochemistry International 15(1): 45-54
Lopina, O.D.; Balanova, L.A.; Manokhina, E.A. 1985: The effect of ATP analogues on ATPase and phosphatase activities of Na+, K+-ATPase for duck salt glands Ukrainskii Biokhimicheskii Zhurnal 57(2): 19-24
Vasilenko, T.F.; Pisareva, L.N.; Skvortsevich, E.G. 1982: Effect of pH on ATPase activity and 18-O metabolism catalyzed by membrane preparations of Na,K-ATPase from guinea pig kidneys Tsitologiia 24(4): 492-496
Danylovych, H.V.; Danylovych, I.V. 2007: Effect of nitric oxides and hydrogen peroxide on Ca2+, Mg(2+)-ATPase and Mg(2+)-ATPase activity in myometrium sarcolemma Ukrains'kyi Biokhimichnyi Zhurnal 79(2): 30-37
Silvestrini, M.G.; Sechi, A.M.; Parenti-Castelli, G.; Masotti, L.; Lenaz, G. 1972: Studies of the interaction of mitochondrial ATPase with submitochondrial membranes Italian Journal of Biochemistry 21(5): 265-274
Kitamura, S.; Ishihara, Y.; Sasaki, K. 1977: Effect of vasoactive substances on the cyclic nucleotide contents of guinea-pig lung and tracheal tissues. 2. Effect of different doses of vasoactive substances Nihon Kyobu Shikkan Gakkai Zasshi 15(7): 391-398
Chen, D.D.; Dai, D.Z.; Lu, J.; Zhang, X.K. 1996: Propranolol and bepridil attenuating levothyroxine-induced rat cardiac hypertrophy and mitochondrial Ca2+ Mg(2+)-ATPase activity elevation Zhongguo Yao Li Xue Bao 17(6): 516-518
Zimmer, G.; Schraven, E.; Mainka, L.; Trottnow, D. 1982: Electron spin resonance studies on the influence of carbocromen on mitochondria and oligomycin-sensitive mitochondrial ATPase Arzneimittel-Forschung 32(2): 110-113
Monosíková, R.; Breier, A.; Ziegelhöffer, A.; Sima, F. 1991: Comparison of ATP binding in the active sites of (Na+ + K(+)-ATPase, Mg(2+)-ATPase and Ca(2+)-ATPase with low affinity to calcium from cardiac sarcolemma Bratislavske Lekarske Listy 92(3-4): 142-145
Crabb, J.W.; Hanstein, W.G. 1985: Bovine heart mitochondrial F6: HPLC purification, NH2-terminal sequence and the possible structural relatedness to other components of ATPase complexes Biochemistry International 10(3): 385-393
Mansurova, S.E.; Dukhovich, V.F.; Spiridonova, V.A.; Shakhov YuA; Velandia, A.E.; Khrapova, N.V.; Tikhonov, A.N. 1984: The effect of phospholipids on the activity of mitochondrial pyrophosphatases. Lipidized soluble mitochondrial pyrophosphatase: the coupling factor for oxidation and phosphorylation Biochemistry International 8(6): 749-755