Selective proximal vagotomy and pyloroplasty--long range experiments in the rat
Hellerer, O.; Aigner, R.; Bauer, H.
Zeitschrift für Gastroenterologie 18(2): 74-80
1980
ISSN/ISBN: 0044-2771 PMID: 7385935 Document Number: 155066
Following the evaluation of the result of SPV in rats by determination of reduction of acid production the effect of the same operation on gastric motility was compared to that obtained with both SPV and a simultaneous pyloroplasty in a one year study. As demonstrated radiologically, with SPV alone gastric stasis resulted in a greatly enlarged stomach with a high percentage of peptic ulcers. Animals who had SPV together with pyloroplasty showed good emptying of the stomach with few ulcers. In this group the incidence of ulceration was reduced from 45% to 5,5%.