Haloperidol stimulation of prolactin secretion: how many blood samples are needed to define the hormone response?
Rubin, R.T.; Forster, B.
Communications in Psychopharmacology 4(1): 41-47
1980
ISSN/ISBN: 0145-5699 PMID: 7398241 Document Number: 154461
Haloperidol, 0.5 mg, was given i.m. to 18 normal men and i.v. to 7 normal men. Prolactin levels were measured in blood samples taken every 20 min for 1 h before and 7 h after drug administration. Correlation analysis indicated that sampling for 3 h post-drug sufficed to accurately reflect the full 7 h prolactin response profile, and log transformation of the prolactin data enhanced the strength of the correlations.
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