Sulfated glycosaminoglycans of human aorta: chondroitin 6-sulfate increase with age

Toledo, O.M.; Mourão, P.A.

Biochemical and Biophysical Research Communications 89(1): 50-55

1979


ISSN/ISBN: 0006-291X
PMID: 475815
Document Number: 154216
The proportions of chondroitin 4 and 6 sulfates of intima and media layers of normal human aortae vary with age. The 2 isomers are in approximately equal amounts in aortae of young individuals, while the 6-sulfate is more abundant in those of adult individuals. This increase of chondroitin 6-sulfate is more pronounced for intima and media obtained from atherosclerotic aortae.

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