The efficacy of ustekinumab in psoriasis
Famenini, S.; Wu, J.J.
Journal of Drugs in Dermatology Jdd 12(3): 317-320
2013
ISSN/ISBN: 1545-9616 PMID: 23545915 Document Number: 15387
Psoriasis is an immune-mediated cutaneous disease affecting 2% of the worldwide population. While topical therapy, phototherapy, oral systemic therapy, and biologic agents have been used, the treatment of psoriasis still remains a challenge. Ustekinumab is a biologic therapy that provides a novel avenue for management by blocking interleukin-12/23. The purpose of this article is to review the mechanism of action of ustekinumab and its efficacy in psoriatic patients. The use of ustekinumab in other immune-mediated diseases is also discussed. It is our goal to provide dermatologists with the knowledge to enable them to incorporate ustekinumab into their practice.
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