In vivo activity of a nonspecific T cell-replacing factor
Kindred, B.; Bösing-Schneider, R.; Corley, R.B.
Journal of Immunology 122(1): 350-354
1979
ISSN/ISBN: 0022-1767 PMID: 153929 Document Number: 152630
Nonspecific T cell-replacing factors prepared as supernatants from mixed lymphocyte cultures or concanavalin A-stimulated spleen cells are active in vivo iv injected into nude mice at least 3 days before antigen. The supernatants appear to act by enhancing the week IgM responses that occur in untreated nudes. Secondary responses and IgG antibody were not found.
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