The metabolism of aspartate in infant and adult mice
Oppermann, J.A.; Ranney, R.E.
Journal of Environmental Pathology and Toxicology 2(4): 987-998
1979
ISSN/ISBN: 0146-4779 PMID: 448259 Document Number: 152450
Plasma concentrations of aspartic acid -L-aspartate, these rates were similar in 15 day old and adult mice. At 1000 mg/kg, the rates of 14CO2 excretion, as percent of dose, were depressed during the first 30 min after oral and i.p. administration of the compound to both age groups. This inability to metabolize high doses of aspartate at the same rates as lower doses may contribute to the elevated plasma concentrations of aspartic acid in animals given 1000 mg/kg.