Modification of catecholamine metabolism in rats by magnesium aspartate hydrochloride
Kietzmann, M.; Kreisner, M.
Deutsche Tierärztliche Wochenschrift 97(4): 177-180
1990
ISSN/ISBN: 0341-6593 PMID: 2351057 Document Number: 349770
The metabolism of catecholamines was studied in rats treated with magnesium aspartate hydrochloride (MAH). For 3 days, MAH was administered via food (1000 mg magnesium/kg food). An enhanced renal elimination of catecholamine metabolites was found in MAH-treated rats as well as in rats stressed by immobilisation. Measured in vitro, hepatic monoaminoxidase activity was enhanced. The catechol-O-methyltransferase activity was not altered. In conclusion, oral treatment with MAH is followed by enhanced hepatic metabolism and increased renal elimination of catecholamines.