Correlation between X-prolyl dipeptidyl-aminopeptidase and serum amine oxidase in serum of patients with post-burn keloids
Nagatsu, T.; Iwase, K.; Kasahara, Y.; Kubono, K.; Sakakibara, S.; Aoyama, H.; Izawa, Y.
Clinical Chemistry 25(3): 376-378
1979
ISSN/ISBN: 0009-9147 PMID: 400439 Document Number: 151499
Activities of X-prolyl dipeptidyl-aminopeptidase (EC 3.4.14.1) and amine oxidase (EC 1.4.3.6) in serum were assayed in two groups of patients, children two to nine years old and adults 23 to 60 years old, with hypertrophic scars after severe burn. The peptidase activity tended to be low initially for several months after the burn, but then returned to normal after six months. These changes were marked in the child group, less so in the adult group. Similar but less-pronounced changes were also observed in serum amino oxidase activity. The two serum enzyme activities showed a significant positive correlation (r = 0.668, p less than 0.001, n = 27) in the patients.