The purine salvage pathway in erythrocytes of psoriatic patients
Partsch, G.; Gatzakis, S.; Eberl, R.; Luger, A.
Zeitschrift für Hautkrankheiten 54(18): 808-812
1979
ISSN/ISBN: 0301-0481 PMID: 539027 Document Number: 151384
Investigations on the purine-salvage-pathway in erythrocytes of 3 patients with psoriasis and of 3 healthy control persons revealed equivocal differences. The transfer of 14C-adenine to adenosine-monophosphat as well as the uptake of 14C-guanine is markedly increased and the incorporation of 14C-hypoxanthine deviates in psoriatics from the controls. A correlation between these findings and the clinical course could not be observed. The paper presents first results of a study concerning the synthesis of nucleotides in the course of the reutilisation of purines within erythrocytes of psoriatic patients.