Standardization of the alkaline elution procedure using X-ray-damaged nuclear DNA
Bolognesi, C.; Cesarone, C.F.; Santi, L.
Tumori 65(5): 511-516
1979
ISSN/ISBN: 0300-8916 PMID: 42176 Document Number: 150393
Structural modification of DNA were induced by X-irradiation of crude hepatic nuclei at various dose ranges to standardize DNA damage evaluated by the alkaline elution technique. This quantitative assay can be used as reference for DNA damage induced by the in vivo administration of mutagens and/or carcinogens involved in the environment.
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