Present-day treatment of dyskinesias
Fonsegrive, J.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 55(1-2): 88-89
1979
ISSN/ISBN: 0037-1777 PMID: 34220 Document Number: 150317
The physiopathological processes involved in the production of dyskinesias will become clearer as our knowledge of neuromediators and their receptors increases. Among centrally-acting molecules, pimozide and the substituted benzamides block dopaminergic receptors only. Tiapride, which is a substituted benzamide, has an original neurotropic action expressed as relaxant and antidyskinetic activity. It is perfectly well-tolerated and is simple to prescribe, which has made it a product for use in general practice where very encouraging results have been obtained, especially in the two cases reported: an elderly patient with buccofacial dyskinesia often seen in this age group, and a patient with severe dopa-induced dyskinesias.