Lesions in lambs experimentally infected with bovine respiratory syncytial virus
Cutlip, R.C.; Lehmkuhl, H.D.
American Journal of Veterinary Research 40(10): 1479-1482
1979
ISSN/ISBN: 0002-9645 PMID: 525867 Document Number: 149980
Three of five lambs inoculated intratracheally with respiratory syncytial virus became febrile and listless and showed hyperpnoea. The lungs had multifocal areas of consolidation, with necrosis of individual epithelial cells of the airways and accumulation of necrotic debris, macrophages, and few neutrophils in terminal airways and alveoli. Pulmonary septa in affected areas were infiltrated with numerous macrophages and lymphocytes. Viral particles were seen as buds on epithelial cells and free in bronchioles and alveoli.