Galactorrhea in sarcoidosis: dynamic studies of prolactin, growth and gonadotropic hormone levels
Caro, J.F.; Israel, H.L.; Glennon, J.A.
American Journal of the Medical Sciences 277(3): 289-294
1979
ISSN/ISBN: 0002-9629 PMID: 110148 Document Number: 149767
Five of 300 women with sarcoidosis had galactorrhea. Basal prolactin levels were mildly but significantly elevated when compared to controls and sarcoidosis patients without galactorrhea. Prolactin levels responded to thyrotropin releasing hormone and L-dopa administration, but not chlorpromazine. Luteinizing hormone and follicle-stimulating hormone concentrations responded normally to luteinizing hormone-releasing hormone in all sarcoidosis patients studied, as did growth hormone to insulin hypoglycemia. These results indicate that galactorrhea in sarcoidosis is an uncommon phenomenon, probably due to hypothalamic dysfunction and associated with mildly elevated prolactin levels.