Electrophysiological aspects of the interrelationship between the normal and hypoxic portions of the myocardium
Bukauskas, F.F.
Kardiologiia 19(9): 95-99
1979
ISSN/ISBN: 0022-9040 PMID: 491392 Document Number: 149604
The results of studying the electrophysiological parameters on the boundary between the normal and the hypoxic area of the myocardium are discussed. The experiments were conducted on isolated preparation of the rabbit atrium with the use of microelectrodes for recording the transmembrane action potentials. The existence of the "maintenance" effect is shown, which is manifested by the better survival of the hypoxic area located nearer to the transitional zone as compared to the survival of a more distant area. The "maintenance" effect is due to the electrotonic interrelationship and to the intercellular diffuse processes of the ions and metabolites. With the continuation of the effect of hypoxia, the transitional zone becomes narrower, one of the causes of which is the disturbed intercellular relationship.