Diabetic ketoalkalosis
Koett, J.; Howell, J.; Steinberg, S.; Wolf, P.
Clinical Chemistry 25(7): 1329-1330
1979
ISSN/ISBN: 0009-9147 PMID: 455654 Document Number: 149282
The usual metabolic derangement in uncontrolled diabetes mellitus is metabolic acidosis, with an increase in the anion gap because of increased ketoacids and lactate. However, diabetic ketoalkalosis may occasionally be encountered, the prominent clinical feature of which is vomiting, with depletion of potassium, chloride, and hydrogen ions. Self-medication with absorbabe alkali may also contribute to the alkalosis. It would be dangerous to treat hyperlgycemic patients with alkali if their condition is ketoalkalosis instead of ketoacidosis.