Smoking and death in Thai diabetic patients: the Thailand Diabetic Registry cohort
Pratipanawatr, T.; Rawdaree, P.; Chetthakul, T.; Bunnag, P.; Ngarmukos, C.; Benjasuratwong, Y.; Leelawatana, R.; Kosachunhanun, N.; Plengvidhya, N.; Deerochanawong, C.; Suwanwalaikorn, S.; Krittiyawong, S.; Mongkolsomlit, S.; Komoltri, C.
Journal of the Medical Association of Thailand 96(3): 280-287
2013
ISSN/ISBN: 0125-2208 PMID: 23539929 Document Number: 14963
To determine the impact of smoking and quit smoking on mortality rate. This prospective cohort was a three-year follow-up of Thai Diabetes Registry project that registered 9,370 diabetic patients from 10 diabetic clinics in tertiary medical centers in Bangkok and major provinces between April 2003 and February 2006. The groups of 7,487 (80%), 1,315 (14%), and 568 (6%) patients were classified as non-smokers, ex-smokers, and current smokers. The crude death rate of ex-smokers (Hazard Ratio (HR) 1.52 (95% CI 1.19-1.95)) and current smokers (HR 1.55 (1.10-2.19)) were higher than death rate of non-smokers. After control for covariates, the HR comparing ex-smokers with non-smokers was not different (1.10 (0.81-1.50)), while the HR comparing current smokers with non-smokers remained statistical significant (1.74 (1.17-2.61)). Smoking increases mortality rate in diabetic patients by about 74%. Quitting smoking decreased mortality rate to the same rate as of diabetic non-smokers.
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