Comparative study of different essential oils of Bupleurum gibraltaricum Lamarck
Gil, M.L.; Jimenez, J.; Ocete, M.A.; Zarzuelo, A.; Cabo, M.M.
Die Pharmazie 44(4): 284-287
1989
ISSN/ISBN: 0031-7144 PMID: 2772005 Document Number: 149
A comparative study was performed of the essential oil extracted from the fruiting apex of Bupleurum gibraltaricum Lamarck (Umbelliferae) collected in different areas within the province of Granada, including the Cazulas mountains, the Balcon de Canales and the Quentar Reservoir. All three essential oils were very similar in chemical composition, consisting mainly of monoterpenic hydrocarbons (43-carene and a-pinene). When anti-inflammatory activity against both acute (carrageenin-induced plantar edema) and subchronic inflammation (granuloma technique) was assayed, quantitative differences came to light: the essential oil of the Cazulas Mountains population was most .6 ctive against acute inflammation owing to its high 43-carene content, whereas the Quentar Reservoir essential oil of B. gibraltaricum was most effective against granuloma induced inflammation.
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