Establishment of cell lines from the wild rodent Millardia meltada and tests for endogenous virus

Sugiyama, H.; Yutsudo, M.; Toyoshima, K.; Yosida, T.H.; Murata, Y.

Gan 70(3): 297-303

1979


ISSN/ISBN: 0016-450X
PMID: 223935
Document Number: 148754
Four cell lines were established from the wild rodent, Millardia meltada; an untransformed cell line (MM-D), a non-producer (NP) cell line transformed with murine sarcoma virus (MM-CL4), and SV40-transformed cell lines (MM-8 MM-663). MM-D is epithelioid and contact-inhibited, whereas MM-CL4, MM-8, and MM-663 are fibroblastic and grow piling up. No endogenous virus was induced in Millardia cell lines by a long-term culture with various inducers. Millardia cell DNA has no nucleotide sequence homology with cDNA of either murine leukemia virus or rat endogenous virus.

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