Establishment of clonal cell lines, with or without cartilage phenotypes, from a hamster mesenchymal chondrosarcoma
Fujisawa, N.; Sato, N.L.; Motoyama, T.
Laboratory Animal Science 41(6): 590-595
1991
ISSN/ISBN: 0023-6764 PMID: 1667204 Document Number: 381328
A hamster mesenchymal chondrosarcoma was found in the soft tissues of the cheek pouch and has been successfully transplanted. The tumor was composed principally of two cell types: poorly differentiated mesenchymal cells and focal areas of cells in islands showing cartilaginous differentiation. The clonal cell lines, MCS-1 and MCS-8 which closely correspond to the respective cell types in the original tumor were also established. MCS-1 cells formed an undifferentiated sarcoma in the subcutaneous layer of nude mice and MCS-8 cells formed a chondrosarcoma of a common type.