Microscopic, micro-chemical and fluorescent optical findings in endometrium with a copper-T intrauterine device in situ
Dallenbach-Hellweg, G.; Dallenbach, F.D.; Sievers, S.
Geburtshilfe und Frauenheilkunde 39(7): 575-579
1979
ISSN/ISBN: 0016-5751 PMID: 467951 Document Number: 147709
Sections of the uteri of 10 patients who had used IUDs for several months to 2 years were stained and treated by microchemical techniques to determine DNS, PNS, and copper levels. Examinations by microscope and fluorescent techniques showed no morphological effects of the copper on the endometrium. No deviations from normal DNS or RNS levels could be determined; thus the effectiveness of IUDs cannot be attributed to inhibition of estrogen or gestagen receptors. No elevated copper levels of the endometrium could be determined. It is concluded that the effectiveness of IUDs is due to a biochemical inhibition of implantation within the uterus.